Translational Science Senior Director - Immunology Cell Therapy
AstraZeneca

Job Info

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Introduction to role:

Are you a visionary expert in translational science, with the ability to execute a successful strategy in accelerating the development of cellular therapies for patients with immune-mediated diseases? If you are passionate about transforming the treatment of immune-mediated diseases and making a profound impact on patients' lives, then AstraZeneca might be the place for you! Our ambition is to build an extraordinary organization that accelerates the delivery of transformative cell therapies for patients with immune-mediated diseases. We are driven by courage, curiosity, and collaboration, making bold decisions driven by patient outcomes.

Accountabilities:

As the Translational Science Senior Director, you will be responsible for the implementation of translational and biomarker objectives for cellular therapies for immune-mediated diseases. Your focus will be on ensuring effective collaborations between research and development, establishing strong target-to-disease connections, differentiating AZ cellular therapeutics, and driving translational understanding of clinical trial data. You will be recognized as an authority in translational science and work on difficult drug projects and complex scientific problems, providing solutions that are highly innovative.

Essential Skills/Experience:

• PhD, Medical Doctor or MD-PhD degree required.
  
• 5 or more years of industry or combined academic/industry experience in clinical development or translational science.
  
• Strong knowledge of the pathogenesis of immune mediated disease and the application of cellular, molecular technologies and models to drive program decisions, including those related to supporting value propositions.
  
• Experience in clinical development of T-cell therapy and/or other advanced therapeutic modalities.
  
• Experience in the inflammation and immunology clinical development
  
• Prior experience in BM and precision medicine, IND filing and ideally BAL filing.
  
• Proven ability to learn new information rapidly and effectively
  
• Significant experience in early and/or late phase clinical development.
  
• Significant experience in the authoring of relevant regulatory documents.
  
• Detailed understanding of the full drug development process.
  
• Detailed understanding of translational and clinical research methodology and biostatistics principles.
  
• Thorough command of FDA, EMA, MHRA and ICH GCP guidelines.
  
• Attention to detail, strive to generate high-quality work, and sense of passion and urgency to achieve team and program goals.
  
• Demonstrated experience leading complex projects.
  
• Demonstrated track record in delivering results.
  
• Outstanding verbal and written communication skills.
  
• Excellent analytical, problem solving and strategic planning skills.
  

Desirable Skills/Experience:

• Cross functional team leadership experience
  
• Establishing and leading external partnerships in immune mediated diseases
  

At AstraZeneca, we are at the cutting-edge of science, rethinking the future of medicine. We work on ground-breaking medicine discovery and development from early to late stage, answering some of the most complex unmet patient needs. We are never complacent about scientific discovery and development. Here we are always pushing our productivity, searching for new knowledge and the next breakthrough. We fully embrace a safe space, exercising our freedom to discover and share. You're supported by the team where setbacks are seen as learning opportunities.

The annual base salary for this position ranges from $265,780 to $386,671. However, base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program (salaried roles) or to receive a retirement contribution (hourly roles). Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an "at-will position" and the Company reserves the right to modify base salary (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.

Take the lead to make a bigger impact! Here we need leadership at every level. Physicians who not only have expertise but also the ability to build a business case, engage multiple stakeholders, and communicate effectively with different audiences. With that kind of remit comes great responsibility and the opportunity to make a big impact. Join us and be a part of our journey in transforming lives with science!

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.

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